Chat with us, powered by LiveChat

Being addicted to one substance is already risky, but mixing multiple substances takes the danger to another level. Polysubstance abuse happens when you use more than one drug at the same time or within a short period. This could mean mixing alcohol with prescription pills, combining stimulants and depressants, or using multiple illicit drugs together.

The problem? Different substances can interact in unpredictable ways, making their effects stronger, more dangerous, and much harder to control. The risk of overdose increases and withdrawal also becomes even more complicated.

Polysubstance abuse is a growing issue in the world of drug addiction. And whether it’s intentional or accidental, it’s a kind of situation that demands urgent action. This blog will discuss what leads to this type of addiction and what can be done to prevent or treat it.

polysubstance abuse

Understanding Polysubstance Abuse

If you’re using multiple substances at the same time or within a short period, that’s polysubstance abuse. And it comes with serious risks. In fact, in 2017, nearly three-quarters of cocaine-involved overdose deaths also involved an opioid, showing just how dangerous drug combinations can be.

So why do people end up mixing substances? Maybe you’re trying to intensify a high, manage withdrawal symptoms, or balance out unwanted effects. Other times, it happens without you even realizing it, especially if a drug is laced or misrepresented. Whether it’s self-medication, curiosity, or social pressure, combining drugs (especially the most active drugs) makes addiction more unpredictable and withdrawal much more challenging to manage.

Being addicted to multiple substances isn’t the same as being addicted to just one. If you were only struggling with one, you could turn to a specialist professional for targeted recovery. However, polysubstance addiction is more complicated: Withdrawal symptoms from different drugs can hit at once, and treatment needs to address all of them together.

drug rehab near me

Common Polysubstance Combinations and Their Dangers

Mixing drugs is life-threatening. When you combine substances, their effects multiply, making polysubstance abuse even more unpredictable and dangerous. 

Here are some of the most common and deadly drug combinations.

Alcohol and Benzos 

If you mix alcohol and Benzo medications like wine and Xanax, you’re doubling down on depressants. Both slow down your central nervous system, making you drowsy, disoriented, and more likely to black out. But the real danger? Your breathing can slow to the point where it just stops. 

Alcohol and Cocaine

When you combine alcohol and cocaine, your body creates cocaethylene. It’s a toxic chemical that lingers in your system longer than either drug alone. This puts intense stress on your heart and liver, raising your chances of a heart attack or stroke. It also fuels aggression, reckless behavior, and poor decision-making.

Meth and Other Substances

Pairing meth with alcohol, opioids, or benzos is a dangerous game. You might think mixing a stimulant with a depressant helps balance things out, but in reality, it confuses your body and makes overdose more likely. 

As any reputable meth addiction treatment Los Angeles would confirm, meth already puts extreme stress on your heart. And adding other substances (especially depressants) can make your system crash. Plus, meth fuels impulsive behavior, increasing your risk of dangerous situations, violent outbursts, and long-term damage to your brain and heart.

detox Los Angeles

Finding Help: Drug Rehab and Treatment Options

Struggling with polysubstance abuse? Finding the right treatment can make all the difference. If you’ve been searching for “drug rehab near me,” you already know there are many options. However, the key is choosing one that fits your specific needs.

The first step is clearing your body of substances in a safe and controlled environment. A medically supervised detox Los Angeles provides 24/7 care to help you manage withdrawal symptoms, which can be especially dangerous if you’ve been mixing substances. Detox ensures a safer transition into treatment by preventing medical complications and stabilizing you physically and mentally.

From there, residential treatment offers full-time care, including therapy, medical support, and relapse prevention strategies. If you need more flexibility, outpatient rehab allows you to attend treatment while maintaining daily responsibilities. 

Many rehab centers provide holistic treatment options, incorporating mindfulness, nutrition, and alternative therapies to support long-term recovery. Meanwhile, specialized programs for certain substances (for instance, meth addiction) focus on behavioral therapy and relapse prevention, helping you regain control and build a sustainable, drug-free life.

When searching for rehab centers, look for facilities that offer comprehensive care, including therapy, medication management, and aftercare planning. Make sure it provides a combination of medical support, mental health treatment, and relapse prevention tools.

rehab center Los Angeles

Conclusion

Polysubstance abuse is dangerous, unpredictable, and difficult to overcome alone. 

Mixing substances increases the risk of overdose, severe withdrawal symptoms, and long-term health complications. Still, recovery is possible with the right support. A structured treatment plan, including detox, therapy, and relapse prevention, can help you break free from addiction and regain control of your life.

If you’re ready to take that first step, Restore Center, the best rehab center Los Angeles has to offer, provides comprehensive care tailored to your needs. Reach out today.


Insurance can cover up to 100% of treatment


We Accept Most Major Insurance Companies. We accept other forms of payment to make treatment affordable for yourself or a loved one